I loaded the front page of Mangadex and it made 114 web requests including 10 first-party XHR requests, 30(!!!!) Javascript resource requests and somehow 4 font requests, without me interacting with the page. Clicking one of the titles on the front page resulted in nearly 40 additional requests.

Perhaps if you are limited by requests per second you could consider how many requests a single user is making per interaction, and if this is a reasonable number.

The website is impressively fast though, I'll give you that.