Surely some goals can bring happiness when they are achieved? I have made some things that I like, and I am happy when I recall that I made them myself. Or if your goal is to cure cancer, and you succeed, wouldn't that bring you happiness? Sure, you can set other goals for yourself, but that doesn't erase the satisfaction.

Either way, my point was that if your goal is to leave a permanent, meaningful mark on the universe, first, that's borderline delusional, second, the actualization of the goal is basically infinitely far in the future. Personally I'd rather pursue goals that can be achieved within my lifetime and aren't some crazy improper integral over the lifetime of the universe...