Does it exist a single long period during human evolution when people stand in place for 40 hours a week
What about period when people sat 40 hours a week at the desk? It didn't happen either.
What about period when people sat 40 hours a week at the desk? It didn't happen either.
To answer your question I think that sitting 8 hours every day is not very healthy, but it's far better than standing 8 hours. Break long period of sitting with some walking, stretching or some light exercise, and you would eliminate almost all negative effects of prolonged sitting.