Don’t forget Vioxx!
> Five years after Vioxx's launch, Merck withdrew the drug from the market. By that time, Merck had sold billions of dollars of the drug worldwide.
[1]: https://www.npr.org/2007/11/10/5470430/timeline-the-rise-and...
Great example.
Nothing here is an indictment of vaccines per se. However, it is legitimate to have concerns over a process the rules stated at the outset were thrown out, possibly for personal profit and political motivations.
Also, see https://news.ycombinator.com/item?id=28280087 for a link to an articulate consideration of a number of concerns regarding this approval.