Thanks for your candor. It would be interesting to see what positive effects can be achieved for what types of patients at various different dosing levels.

I'm not at a weight where I'd want to add additional cancer risk in order to lose weight, and unfortunately the data on this sort of incremental risk probably takes decades to be fully realized. Perhaps I'd feel comfortable taking a smaller dose if there were a shorter-than-ideal track record of people taking larger doses without much additional risk.