Not sure about how the situation is in the States but the people driving those quick delivery vans over here in Eastern Europe (and over much of Western Europe, too, my country is in the EU so their companies can send them anywhere from Varna to close to Gibraltar at a moment's notice) have a very, very tough life, with many of them doing 14-16-hour driving stints. Apart of the huge stress that entails and the accompanying health conditions many of them also get into fatal road accidents because of said overwork and tiredness.

Fortunately the work of drivers driving big lorries is more tightly regulated with the worker's wellbeing also taken into consideration so that there's a fixed time interval per day you are allowed to drive, after which you have to literally stop at the first parking spot at the side of the road, no matter what the boss screams in your phone from half-way across the continent.