Making hardware that'd take advantage of this simple instruction set might have some interesting results.
With a friend we "invented" exactly what you described. Our original idea started as a joke to make a processor with a single instruction,and when we thought of having registers that would systematically be updated with the results of different operations on two operand registers we understood we could actually do it. So we did. It was a bit tricky and quite slow but it was a lot of fun and we still managed to beat the second at the end =).