"Stripe relies heavily on gems with native extensions, and as you can imagine, a multi-million line Ruby codebase over time starts to depend on Ruby-the-implementation, not just Ruby-the-language.
I get it, this is a big one. How big though? I wish as a community we had a list of important gems that have an extension, maybe with a combined effort we can port them to the JVM or whatever else so people can switch between JRuby/Truffle/MRuby with relative ease. I know about the big ones: Of course Postgres/MySql gems come with extensions and probably most Ruby web servers. But what else - what are the big ones?