Browsing to all developer studios websites for my favourite 50 steam titles is a bit tedious... in other words... I'm lazy.
For those who are not (always) on steam there's also the original wine:
Unless you don't have a magically compatible hardware setup. On my laptop like half my Steam library won't start, only shows a black screen or crashes instantly. Not even all official Linux releases reliably work. The last time I tried Ubuntu I couldn't even install Steam out of the box. Yes, Steam+Proton has improved the situation immensely. It's still a different kind of experience than on Windows, though.
I just went the console route. Not perfect, but I like that it basically guarantees the hardware will be compatible with new games for 5+ years. The slightly better visuals aren't worth it to me, most games look good enough nowadays (or rather, the best-looking games tend to not be the most enjoyable ones on average).
Of course this presupposes you got NixOS set up at all in the first place. And I'm not ENTIRELY sure I'd recommend it for your daily driver. But a friend of mine talked me into it all; and despite the warts at times it just seems like it's the least worst distro (to praise it with faint damns)
I moved to flatpak for Steam on NixOS and couldn't be happier, except now the latest proton uses flatpak under the hood and flatpak doesn't support nested containers.
I hear the flatpak-based Proton works much better (and that makes sense) but I still have some titles that are broken with it but work with older versions.
For non-game software (and even some games), https://alternativeto.net/ can help you easily find Linux-native alternatives to software that you know the name of from other platforms. Also great for finding interesting software alternatives for your other platforms (iOS, Androin, Win, Mac, etc) too.