> A "microdose" is enough to alleviate symptoms of depression without risking one's psychological stability.
Not only the body weight of the person is going to matter, yields of active substance varies heavily and there is no consensus on what a microdose is. Cut-off can be as low as 0.2 grams.
Psychedelic use is correlated with an increase in neuroticism though, and not as a function of the badness of the trip. Plus in a susceptible person even 0.5g can trigger a first psychotic episode.
I find such claims of safety unfoundedly bold and honestly irresponsible.