Currently, not much. We’re Galileo grinding lenses at home.
Theoretically? Everything from a whole new mode of active sensing, e.g. deep into the Earth and/or Sun, all the way to communications. Being able to directly measure gravity also lets us do new classes of experiments (not yet, but if we can measure more sensitively). We don’t know what we don’t know when it comes to gravity, so that’s another pot of potential.
Less fantastically, these are immensely precise instruments. The manufacturing methods and know how will almost certainly translate to other domains.
* https://en.wikipedia.org/wiki/Telescope#By_spectrum
This will allow measurements of another type of wave.
* https://en.wikipedia.org/wiki/Gravitational-wave_astronomy
Using the time delta between detecting the same events at different detectors around the globe, we have inferred the directions the signals are coming from.
The intensity curves of the events tell us details about the masses and other characteristics of the colliding object. Also over time the distribution of their masses and other characteristics will give us information about the populations and distribution of these objects, which can help validate our theories of star, neutron star, black hole and galaxy formation.
My preferred argument is, if we can spend billions on trivialities like carbonated sugar water and computer games, as a civilisation we can afford basic science research. It’s not actually all that expensive in the grand scheme of things, and cutting science would not necessarily have any impact on funding for the alternative things (world peace, feeding the poor, etc) people who complain about such funding want. If they want to complain about waste they are picking a particularly poor target. A bit of a tangent, as the head comment wasn’t actually making this complaint.
Get them working well enough and we might be able to see the cosmic gravity wave background. That might let us see how/if the big bang actually happened, pre-inflation.