Homoiconicity is an ill-defined concept. If you take every subjective feature from it, all it implies is that you are able to cut your code into well defined AST structures (what all languages have, but for some it's easier than for others).

So, yeah, anything people do with Lisp could be done for any other language, it only requires more complex tooling. How much more complexity depending on the language, and it varies from "barely perceptibly more" into "that's completely not practical".