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Comment by etaioinshrdlu | Hacker News Reader

I have been heavy dosing magnesium (glycinate, citrate) for years and am still a nervous wreck. Your mileage may vary.

I’ve recently switched to magnesium L-Threonate which has shown to be far more effective at being absorbed by the brain and I’ve found myself far less anxious in social situations.

The L-Threonate compound was developed at MIT specifically for better brain absorption. Source: https://dspace.mit.edu/bitstream/handle/1721.1/96066/Slutsky...

I found that mag l-threonate helps me fall asleep after an anxious afternoon/night but I'm groggy in the morning. Also, I've read anecdotal reports that after a couple of weeks of regular use, the effect flattens out (sorry, too lazy to search for those reports) and one has to take a break for the effect to return. Have you noticed anything along those lines?

For me, the effect is less (or possibly just less noticable) after a few weeks. But some coffee or tea gets me going pretty quickly and the effects wear off.

I've always been a slow morning person, so 30-60 minutes to start feeling normal is on par for me, so it doesn't really affect my timetable, but you may have a different schedule in mind.

My morning bowel movements when I take magnesium l-threonate are amazing, however, which used to slow me down even more on a typical morning.

If you're interested in testing a further nutritional approach, I suggest the stack suggested by the late great Charles Poliquin.

The stack: https://www.facebook.com/StrengthSenseiInc/videos/anxiety-so... (sorry for FB link)

Background on Poliquin: https://tim.blog/2015/07/21/charles-poliquin/

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