IIRC, most configuration of electron microscopes tend to lyse cells because of the environmental conditions of hard vacuum and high charge.
Then some instruments came along that took advantage of lysing cells for analysis: flow cytometry.
If you can look at cells without going full-power Death Star on them, that sounds damn useful.
---
I anticipate Applied Science will build one in his garage over the weekend and apologize for not making it 2 orders-of-magnitude more sensitive than UQ's. :bow before the might of this over-achiever who ships, a hacker as salty as my HP 48G/X: