I frankly disagree that antiinflammatory drugs having "long term costs". I'd be very interested if you have a paper to back that claim up. A couple decades ago it was common for rheumatic patients to end up in wheelchairs. Today that's very uncommon. I agree that most antirheumatic drugs, and most drugs in general, treat the symptoms rather than provide an outright cure. But that's enough to drastically reduce disease severity and increase quality of life. Actual cures might be ideal but we are far from there research-wise - at least for most rheumatic conditions.