This is the 21st century. There's no one weird trick to being healthy, successful, having a high quality anything.
Biological systems are complex and don't have a single variable which needs optimizing, they have many, need many, and every variable with leverage needs to be thought as a part of a whole.
For example if someone wrote "Is Exercise the key to a healthy brain", it sure can look click-baity, but in practice it's a tried and tested lever to improve brain health. Sure, you can say "oh there are 10,000 other things that influence brain health and it's a very complex inter-connected system", but you miss the fact that not all of those 10,000 things are equally deserving of your time or even under your influence. In fact, things like exercise or meditation can fall under the "weird trick" category.
If focusing on mitochondria's health falls under that "outsized effect" category is the thesis of the article and remains to be seen if it can be included in the same category as other tried and true influential levers.
We see this over and over in press releases when new research is focused on one mechanism (e.g. mitochondria). To me "weird tricks" that capture whole body or lifestyle changes are at least worth paying attention to. While "weird tricks" in the name of a single biological mechanism are indeed overblown (but still worth knowing if you're in to that sort of information).
Whether mitochondria is just one mechanism or more of an over-arching one is what research is all about. For example, HRV feels like on obscure metric out of 100s of metrics. But it has been shown to now have hundreds of mental and physical benefits including longevity, that we don't necessarily understand why but it still has risen to the top. Same for intermittent fasting and so on. These are indeed "weird tricks" in a pretty literal sense but they do the job in predictable and often dramatic ways.
(Edited to correct terminology)
Humans have a very surface level understanding of the our internal systems that make our bodies work, we know next to nothing about most of the ecological and environmental systems we also rely on. Everything from our external environments, to the things that enter our bodies to all the things that live in and on our bodies, all the things play a part in our health and functioning.
It is possible that there are many facets of reality that are simply outside the comprehension of human brain. In fact, is is likely that most reality is outside our comprehension.
It's possible that there are many facets of flight that are simply outside of the comprehension of human brain."
You could make this exact same argument for all technology until it's discovered.
Yet, people love "one trick" wonder -- just go on YouTube and search for "golf swing" or "lose fat", it's so easy you don't even have to leave the house.
That said, +1 for holistic approach.