There are many things that fundamentally defy any form of computation. Things which cannot create mathematical formulae to represent, nor create algorithms for.
For a major example, we cannot translate the mental activities of conscious, aware living beings into any sort of computable form, as these activities are not algorithmic in nature. They aren't random, nor deterministic ~ rather, they are indeterministic, following no rigid patterns.
Even the most complex, complicated computer program follows an algorithm, which is ultimately deterministic. Even if you throw in some random inputs at some parts, the algorithm still acts deterministically. Perhaps the only really indeterministic part in an algorithm's behaviour might be hardware level bugs and errata which interfere with the otherwise very predictable algorithm.