No, because – as I mentioned above – the uploaders would still maintaining all kinds of technology to monitor and control the outside world in order to ward off any threats (natural disasters, sabotage from the non-uploaders) to the computing infrastructure on which the simulations are running. If the majority of society chooses to upload, then that suggests that such protective infrastructure is already so stable and advanced, that the non-uploaders would be powerless to simply "pull the plug".