I mostly agree split keyboards aren't as good for one-handed usage where keys across the whole board are needed. Maybe for this usage something like the Kinesis Freestyle is more usable than a small keyboard like the Corne, but using the RHS will still suffer.
I don't think that makes the keyboards bad; it's just they're better suited to usages where you can use both hands at once compared to one-handed usage.
For "using function keys a lot", I don't think having the function keys behind a modifier is slower or inherently worse than having extra keys for it. - If you prefer to have the extra keys and don't mind moving your hand, that's fine. - But since many of these keyboards are designed with "minimize hand movement" in mind, it's coherent for the designs to omit the row of function keys (and even the row of number keys).
There are a handful of designs which prioritize number of keys over reducing hand movement. e.g. BFO9000 https://keeb.io/products/bfo-9000-keyboard-customizable-full...