Unless your company requires you to use Microsoft Defender for Endpoint on Linux (https://docs.microsoft.com/en-us/microsoft-365/security/defe...), which is supported on RHEL, CentOS, SLES, and a few others, but not openSUSE ("distributions [...] that are not explicitly listed are unsupported, even if they are derived from the officially supported distributions").
Even for the Microsoft software that "supports" OpenSUSE, historically that support was by expecting OpenSUSE users to use their RHEL packages which didn't always work well. [1] [2] (I don't know if the problems are still there, because I switched to the Docker image for `az` and stopped using `powershell`)
What do they actually do, other than actually increasing attack vectors?
That's the main-point of having a Antivirus :-)
But if one needs to check for (windows) virus's do it on the file-server/email-server level and not on the linux endpoint, use something like selinux and a host intrusion detection system instead, it's just a waste of money and power to use a antivirus...even on a good maintained windows.