Presumably, every space ship needs bulletproof software routines for calculating trajectories, making burns at the right time, etc- a combination of real time hardware control and sophisticated math.
But presumably, ships need to get updated in-flight, and upgraded routinely, and presumably, it doesn't make sense for your own ship to drift too far from the common development tree. This is starting to become a major software engineering problem- how do you manage a fleet of ship firmwares across a solar system?