OTOH, it being a standardized thing, a spammer would absolutely just strip that plus part off. Better do it secretly like a catch-all.
The '+' alias feature is a fairly common configuration, though, so for source labels it's better to either treat all unlabeled messages as spam or else use a more opaque labeling scheme (unique-hash@example.com) which doesn't hint at an alternative untracked email address.
That whole setup for tidiness is broken the moment a desired website does not accept an alias in your address, of course.
Why? They don't care about protecting the business interests of wherever they got that address from, and it's not like stripping the plus off will meaningfully increase the success rate.