It might be an idea to decide as a community that the time of completely unassisted speedrun leaderboards has passed, and shift the competitive element of your community to technological advancements in TAS tools.
In a TAS, the game is being played by the computer using a series of pre-programmed inputs. The fun in TASing is creating the most optimized set of inputs that completes the game in the shortest amount of time. There are often precise one-frame tricks or inputs that would not be possible for a human to perform but can be done easily when you can fully control what happens on each individual frame of gameplay.
Mixing TAS and non-TAS runs doesn't make much sense as humans would never be able to compete.
Of course, there are folks who can do those frame perfect tricks, but if it ever does come to contention, then asking them to perform said trick live seems like a pretty easy way to confirm.
Then again some people still enjoy watching professional cycling so maybe it will be fine.
It brings up the immensely boring tarpit of "What is sport?"; I don't care that e-bikes with enough power to climb Alpe d'Huez exist; It doesn't invalidate the cyclist's achievements (but doping does, and why is that?)