What have you found to be the best way to implement a REST interface? I noticed the @ajax_request shortcut but nothing response code specific. I've been using Django-Piston which has been... challenging at best.
Otherwise Django-Piston sadly is the way to go.
I'm looking at ModelResource as my example.
If you aren't working with a NoSQL database or a search engine, or grabbing data from an tertiary resource then the sheer complexity found in TastyPie might not be for you.
Django-Piston doesn't offer many features, but its dead simple in its usage.