The think with an Anandtech chipset review is the faster chipset doesn't have big negatives unless power consumption is a major concern.
The excessive weight of these modern 50mm lens can be a real detriment to getting better photographs. It makes you less mobile, and you can only carry so much weight. If you're carring 10x more weight for your 50mm lens than an older design that is 95% as high quality you inevitably have to leave something else out of the pack.