Started supplementing with NMN and NAD+ after coming across David Sinclair’s research and book.
I injured my knee in a motorcycle high side, and seemed to develop chronic osteoarthritis in the joint.
For 2 years I had dealt with this chronic pain and weakness that was only mitigated by leg/rehab exercises. However, the dull pain would come back if I stopped.
After taking NMN/NAD+ orally (1 pill every few days) I noticed that for the rest of the day inflammation was very much reduced for me - especially in my knee. A few months later now my knee is a lot better and I haven’t been taking the supplements.
I like Sinclair’s research a lot, and my anecdote aligns with many of the results anecdotes he has shared. Maybe my knee just healed naturally, but I think there is something here.