If a newspaper or online magazine had traditional ads that were embedded in the page as static images (no distracting video please) then I'd leave my ad blocker off.
True, those are not targeted ads, they are sponsored content, but I wouldn’t even bother setting up my adblocker, had they made them less annoying.
To me though, sure, show me ads, fine, whatever, but don't build them around a profile of me to try to manipulate me directly based on my potential interests and behaviour. Any time I can disable any "personalisation" of ads, I do.
I think there's a bit of a language barrier. What advertisers mean when they say "personalized" or "relevant" is not the same as what their audience means when they use the same words. I find advertisers often mean "what you looked at but didn't buy," but I think most consumers mean "what is likely to interest me."
My opinion is, if DDG is showing me some ads based on my search keywords (which is sort personalised) so they can make some money out of their not-so-bad service? Fine by me.