The main difference here is modality of use -- taking something, once per day, in controlled doses, is very very different from taking something until you feel good. With a prescription, you also have a steady supply and no need to commit crimes to keep up your supply. So the societal problems from drug abuse, like overdose, increased criminality, and breakdown of relations don't happen with prescription drugs to the same extent, even if it's the same substance. Look at when the opoid crisis became a crisis -- it was when cheap, easy opioids stopped being available.
It's almost like addicts are self-medicating and we should give them a legal, prescribed supply of medication.
> Look at when the opoid crisis became a crisis -- it was when cheap, easy opioids stopped being available.
What? In high school (20 years ago, Central PA) I knew zero people who used opiates. A few years later I knew people who made trips to Philadelphia. Now they're available everywhere. Perhaps the flow of pill scripts slowed, but fentanyl filled that gap.
Here is an interesting look at the differences between ADHD medications: https://astralcodexten.substack.com/p/know-your-amphetamines
Taking more doesn't help your performance, it makes it worse, and you get way more side effects, especially mental side effects. These build up with time.