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Apparently there were studies on adenovirus 5 vector vaccines against HIV in 2007. The vaccine was not successful, but I cannot find any data on long-term adverse effects.

You realize attenuated virusues are also genetically modified? Just via artificial selection.

At least one for Ebola, IIRC.

so, no long-term studies.

The Ebola vaccine in question has been tested in humans since 2015. How long-term are you looking for?

more than 5 years? Cancer risk, etc. is probably something decadal in scope.

Biology doesn't work like that. Certainly not for replication-deficient adenoviruses used by AZ, Gamaleya and J&J.

Plenty of replication deficient things cause cancer, for example asbestos or igf-1. I highly doubt you can rule out accidental crosstalk between elicited immune antibodies and every oncogenic human receptor.