Multi-cursor editing is the fastest way to accurately modify large amounts of text, especially repetitive text. It's well worth learning for your respective editor. Most other editing methods don't come close, especially in terms of speed.
1. select the next 3 occurances of "foo"
2. Press End on keyboard to jump to end of line (even if the part after "foo" was different each time)
3. Start typing away
You can also use the arrow keys to move the cursors, hold shift to do selections, alt + arrow to jump to the next/previous word and so on. Of course all of this can be done with regexes as well, but it takes longer usually to come up with just the right one, even if you are good with them.