The main issues I encounter are about screen sharing. At the moment it does not work for wayland apps (i.e. wayland apps don't show up in the share this). Supposedly there is a way around it, but I've not yet needed to investigate. The other issue is OBS not working (I guess also because of screensharing). And the third issue is some weird bug in Zoom, where if I open the participant or chat window, it becomes extremely laggy. So much so that I can't really type in the chat window because there is such a strong lag, that I finished typing before the word appears. Similarly the video feed becomes choppy.
One other issue was that Pycharm was having issue opening some menus/windows but that seems to have been fixed now.