I recognize that situations and preferences can change, yes. But it would have to be a pretty significant change for me to outweigh 80 minutes on a crowded Tokyo subway, particularly in summer.
FWIW, before the pandemic started, I was not enthusiastic at all about WFH, for various reasons but mostly because I live in a small one room apartment (quite usual here in the inner city in Tokyo). Now, after addressing basic issues to improve the ergonomics of my home office, most of the downsides are gone, and those that remain are outweighed by the prospect of commuting again. Of course, this could easily change if I moved closer to the office (or switched jobs to be physically closer), but considering rent close to the typical business hubs here, that's unattractive financially.
As for isolation: personally, I do a lot of pair programming (whether in the office or remotely), so I don't actually feel isolated at all. If would describe myself as mildly introvert, so YMMV, but I feel like I need to disconnect from people after a day of remote work no more or less than after a regular day at the office.