For example, try going to compass.com and using embedded Street View in Safari. It's nearly unusable.
Sure, you might say Chrome is going to have a monopoly on "making things work nicely with Google Maps/Meet" but then you jump on Firefox and the experience is just fine. Safari's the only one with compatibility issues in my subjective experience.
Microsoft Teams also has missing web functionality specifically in Safari, functionality that works perfectly fine in Firefox and Chrome.
There are many more examples than just these two. Despite being an incredibly popular mobile browser, and being the default browser on macOS, I find that Safari is the only browser that I have to periodically switch away from temporarily in order to get some random website to work properly. If I'm doing critical work like taking an online exam I will always choose Chrome or Firefox because I know I can depend on it working and being properly tested.
At the end of the day, casual users aren't staring at Activity Monitor all day, and for them RAM is "free." I have a Mac with 8 GB of RAM and I've never noticed any slowdown or issue from using Chrome, Firefox, and/or Safari all simultaneously along with many other open apps. I don't have to care about what my OS does to manage memory because it's 2021, not 1995.
I think we all know, of course, that Chrome is Internet Explorer at this point. We are close to another monopoly situation that I'm not confident the US Government will properly address.