I don't think so. Reading a book or watching a show isn't about the fastest route to a conclusion. To borrow a phrase: it's the journey, not the destination.
IE: I'm watching The Crown right now. I've been "spoiled" on the outcome of the show through simple history and cultural knowledge (I'm Canadian). It doesn't make the show any less enjoyable when I know that Diana is going to die, or that Mountbatten was killed by the IRA.