i can usually block those scripts and still have a functioning page
You can think of WebAssembly as another mechanism for executing code in the browser in the context of a web page. JavaScript is still required to (1) load the wasm binary, (2) evaluate it and (3) connect it to DOM APIs or really anything outside of the isolated wasm execution context.
https://github.com/uBlock-user/uBO-Scriptlets
This wont work with webassembly.
executesitefunction.js could arguably be effected, but that relies on a site installing a particular function on window, which isn't required when using JS, and could be still done where the function is backed by WASM
A lot of stubs, a lot of functionality to kill a script when tripping certain trigger action, or force some properties.