3d printing an entire custom graphical plate with text already on it seems more practical in production terms, although of course you would be limited in design terms by the resolution of what you could get out of your printer.
It would be interesting to do 4-color printing on this as well - obviously you would not have fine enough resolution to do a true "screen" but you could do what amount to multicolor woodcuts. Wonder how good the "reproducibility" is, in terms of ensuring that the paper is always accurately aligned/etc. Part of the charm though, I suppose.
Perhaps you could do the block-printing equivalent of "ascii art" and use some pre-printed blocksets which don't correspond to actual characters, but which could be arranged to print some approximation of an image.
Or just ascii art itself although these blocks appear to be fairly big for that.
Pretty neat and fun little idea.