Acclimatisation is real. I've noticed a trend in the UK over the past 20 years or so. Previously many people, like my parents, used the central heating minimally. It would come on in the morning just to take the edge off in the winter. But that was pretty much it. Nowadays people are trying to keep their house the exact same temperature year round. That means it's warm in the winter and (if you have ac) cold in the summer. But people never acclimatise to the outside temperature as a result. So outside always feels way colder than it really should, or way hotter.
This winter I've reduced my study temperature (where I work every day) from 21 degrees to 19 degrees. It didn't take that long to acclimatise and now I'm not only saving money, I'm more closely acclimatised to the outside temperature.
I think ideally we wouldn't use thermostats, but instead use a system that adjusts inside temperature some percentage towards the ideal. So in winter when it's 0 degrees outside it's 17 degrees inside, and in summer when it's 30 degrees outside it's 25 degrees inside. Just think of the savings and how much nicer it will be to go outside when you're acclimatised.