If the slowdown is sufficiently bad and it's happening on Windows then you can always record an ETW trace (https://support.google.com/chrome/a/answer/9025467) and share it with me. My DMs are open: https://twitter.com/brucedawson0xb
I've resolved a few Chrome performance issues due to strangers on the internet sharing ETW traces with me, and analyzing those traces is actually my day job.