Shameless (semi-)self plug: my wife loves putting together DIY escape rooms, and given the current situation she recently made one that can be done completely virtually with little prep:
https://www.thegamegal.com/diy-escape-room-kit-alien-threat/
Five "rooms" (or in other words, five people or small groups) that all coordinate via a video call and each have a mini-site and individual puzzles to solve that build up to the main solution. I think she's pretty awesome and therefore the game is pretty awesome, but I'm a bit biased. :)