If the code is implementing against interfaces, why would late binding mess up your IDE experience at all?
You get the other kind of interface when you want to loosely-couple your code, and so you define interfaces for many classes. Often, there is only a single class that implements the interface in your project, though there may be mock implementations in your test code. Even though there is a single "real" implementation, the IDE can't/won't jump to that implementation in the same way it won't in the first case. This is frustrating though, because it would have worked if you hadn't extracted the interface for improved testability.
The fact our solution has an interface for just about everything for testing reasons doesn’t slow me down even in the slightest when I’m looking through the code.