Drugs can be helpful, but it's important to find a good doctor first. A lot of doctors will just try lots of different meds and see what sticks. When you're dealing with toenail fungus, that's ok, but when it's your brain, the result can be catastrophic. And if the drugs turn out to be wrong, getting off can be a nightmare. Google "brain shivers" for a good example. In my case, CBT has been a much bigger, more lasting help.