I connect from Windows 10 client to a Windows 10 host using RDP driving dual 4K and it feels like native, though I mostly just use single 4K. This it’s my daily driver over a standard UK fibre to the cabinet (FTTC) connection client end to a gigabit connection host side.
I’m generally using office, internet, Windows terminals/ssh, IDEs etc. Very rarely an overly dramatic full page video advert will jolt me back to reality that I’m doing this over RDP.