In the case of 37signals and their product line, there's no fuzziness that they are most interested in their business. They say 'NO' to all but a few of their customer requests and implement the ideas THEY want to implement, WHEN they want to implement them.
Pg says make something people want and will find useful, while DHH says make something you will find useful and stick to your intuition.
I think 37signals and their manifesto make them much happier than trying to please others.