Shockingly the human genome itself has not been fully sequenced, despite the human genome project completing years ago [0]. There are difficult to map regions of the genome, some of which are interesting. Only recent advances in long read sequencers have helped to solve some of these issues [1].

For the future to truly be amazing with one sequencing the lab prep, chemistry, and equipment required needs to advance. Oxford Nanopore has some advancements here [2] but it's still a ways to go before you could have a sample prepared as easily as an ultrasound or x-ray.

[0] https://www.statnews.com/2017/06/20/human-genome-not-fully-s... [1] https://www.ecseq.com/support/ngs/are-there-regions-in-the-g... [2] http://nanoporetech.com/products/voltrax