Nodejs is incredible fast for a interpreted language. It is only ~4 times slower than Rust and only a bit slower than Go or Java (compiled GC languages) in the benchmarks. Compare that with Python 3, also interpreted but ~30 times slower than Rust.

I know that Python 3 can do some runtime stuff that Nodejs can't, but I wonder whether that's worth so much performance. Maybe if the answer is that you would include C modules in Python if you need the speed, but I don't know if that's a good answer to the problem.