That's why there's a trend toward ortholinear keyboards at the small(est) end of things. It helps that they're also fully programmable.

Want a numpad? Switch to a different layout on the fly and have a numpad where you want it. Arrow keys? F-Keys? Why not have those on home row with another layout!

It can get gimmicky, but the impetus for it is that less overall finger/wrist movement == more ergonomic but I'm not fully convinced. Instead, I just prefer everything I can get on home row.