Hipster burgers are thicker with higher fat content, guaranteed to be more calories. They also usually have a brioche bun with more calories and a huge serving of "aioli" (mayo).
Higher fat content also means more satiating, so you won't feel hungry shortly after eating. If all of the ingredients are healthier than McD, that should be a clear win. OTOH I don't think burger is a good choice for a healthy meal anyway. I'd choose a hipster version primarily for taste and aesthetics.