You're going to need a whole new breed of faculty to support this. Tons of schools are still shackled to Office. I have tons of PowerPoint slides that look like crap when opened with Google Docs, and look even crappier when exported from Google Docs so I can share them with people who refuese to use the cloud. The same holds true for Word and Excel documents.

I'm not saying it's impossible... but I don't think the current education system is ready for that. Explain to the average college student (a non-techie) why the slideshow their professor gave them won't open on their Google laptop.

OTOH, our school is experimenting with lab virtualization, so all you need is the frontend software. I can run full Excel on my iPad, so maybe that's a usable route.