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Comment by Enginerrrd | Hacker News Reader

>The subjects were placed in a pressurised chamber and given pure oxygen for 90 minutes a day, five days a week for three months.

>It is understood that instead the effects were the result of the pressurised chamber inducing a state of hypoxia, or oxygen shortage, which caused the cell regeneration.

This article is garbage. What they are reporting makes no sense. Putting people in a HYPERbaric oxygen chamber shouldn't make them HYPOxic, which is what they are suggesting causes the age-reversing effect.

This fundamental misunderstanding gives me little faith they have in any way correctly interpreted and reported on the study.

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Didn't read this article, but saw this in another article:

> Every 20 minutes, the participants were asked to remove their masks for five minutes, bringing their oxygen back to normal levels. However, during this period, researchers saw that fluctuations in the free oxygen concentration were interpreted at the cellular level as a lack of oxygen – rather than interpreting the absolute level of oxygen.

> In other words, repeated intermittent hyperoxic (increased oxygen level) exposures induced many of the mediators and cellular mechanisms that are usually induced during hypoxia (decreased oxygen levels) – something Efrati explained is called the hyperoxic-hypoxic paradox. “The oxygen fluctuation we generated is what is important,” he told The Jerusalem Post. “During this process, a state of oxygen shortage resulted, which caused cell regeneration.”

https://www.jpost.com/health-science/israeli-scientists-say-...

Why would oxygen shortage lead to cell generation ? If I regularly choke myself, will I end up living longer ?

That's what pranayama says

Hormesis is a fairly common theme in human biology.

We seem to be at our best when under mild stressors.

> Hormesis has been observed in a number of cases in humans and animals exposed to chronic low doses of ionizing radiation. A-bomb survivors who received high doses exhibited shortened lifespan and increased cancer mortality, but at low-dose radiation the ratios of cancer deaths in A-bomb survivors are smaller than those of Japanese averages

(from Wikipedia)

I had never heard of hormesis before. Fascinating and a bit counter intuitive

You could just live at a higher altitude.

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