Stories like this can be really misleading because large companies almost can't help but trick themselves into financial shenanigans. It's very possible that Dropbox just spent $100M upfront to start saving $35M / year relative to AWS current prices... but discovers in year 3 that they are no longer saving money because AWS has reduced prices via their own R&D, which is spread over a massively larger customer base.
Now, because Dropbox is a storage company, it may well make since for them to continue R&D and try to keep pace with AWS, at least for their own needs. But 99% of other companies - of any size - would likely fall on the wrong side of the scenario above.